Words similar to lethality
Example sentences for: lethality
How can you use “lethality” in a sentence? Here are some example sentences to help you improve your vocabulary:
Acute lethality is an obvious and easily observed effect which accounts for its wide use in the early period of evaluation of the toxicity of pure compounds and complex effluents.
Additionally, unlike the spatially restricted expression of mCul1, the strong Cul1 mutant alleles result in lethality.
Deletion of pcu1 and pcu3 results either in lethality or in severe growth retardation, respectively [ 6].
Since TNFRSF induces cell death by causing an efflux of glutathione (GSH) in other cell types [ 42 ] we sought to determine if pretreatment of CLENDO cells with GSH would attenuate lethality associated with TNFα treatment.
In contrast, dark-grown seedlings undergo skotomorphogenesis (or etiolation), typified by elongated hypocotols and closed cotyledons [ 1 ] . COP1 was first identified through genetic screens as a negative regulator of light regulated development in Arabidopsis [ 2 ] . Arabidopsis cop1 mutant seedlings are constitutively photomorphogenic even when grown in the dark, and the severe cop1 mutants cause lethality in the late seedling stage, indicating that COP1 is essential for plant development [ 2 3 ] . Arabidopsis COP1 (Arabidopsis thaliana COP1, AtCOP1) is essential for the proteasome-dependent degradation of two transcription factors, HY5 and HYH [ 4 5 ] . These two homologous bZIP-type transcription factors directly interact with AtCOP1 and are capable of binding to light-responsive promoters to activate the transcription of many target genes [ 5 6 ] . Genome wide micro-array analysis shows that AtCOP1 regulates most, if not all, of the light-responsive genes under various light conditions [ 7 8 ] , substantiating the notion that AtCOP1 functions as a crucial developmental switch through targeting key transcription factors for degradation, thereby controlling the light-responsive gene expression and photomorphogenic development.
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