Words similar to lesions
Example sentences for: lesions
How can you use “lesions” in a sentence? Here are some example sentences to help you improve your vocabulary:
The positive immunostaining for p53, iNOS and VEGF was observed in the gastric epithelial cells and cancer cells with different rates in the lesions of CAG, DYS, IM and GC.
COX-2 is an inducible enzyme upregulated in inflammatory states [ 20 21 ] . Notably, many NSCLC and what have been characterized as "premalignant" lung lesions have been shown to constitutively express the COX-2 enzyme and produce prostaglandin E-2 (PGE-2), the primary product of the COX-2 pathway [ 22 23 24 25 26 ] . Importantly, PGE-2 production by tumor cells has been linked to tumor-induced immunosuppression in NSCLC [ 2 3 4 5 ] . PGE-2 has been shown to directly suppress T cell mediated immunity, the primary effector against tumor cells, at a variety of levels [ 2 3 4 5 6 7 ] . Further, PGE-2 has been shown to induce the IL10 in mononuclear cells [ 4 5 ] . IL10 is a prominent immunosuppressive cytokine that may have a dominant role in preventing innate antitumor responses in the NSCLC environment [ 2 3 4 5 ] , [ 8 9 10 11 12 13 14 15 16 17 18 19 ] . Among myriad suppressive effects on T cells and antigen presenting cells, IL10 is known to inhibit IL12 production [ 14 15 16 17 18 ] . IL12 plays a key role in the initiation and potentiation of cellular immune responses and alteration of the IL12 producing function in circulating mononuclear phagocytes may be a critical factor in suppressed T cell immunity to NSCLC [ 27 28 ] .
Lesions in the cell bodies of dopamine (DA) neurons [ 10 ] as well as in the terminals located in prefrontal cortex [ 11 ] result in cognitive deficits in executive function tasks.
These lesions tend to occur very rarely in the general population, but may occur with a high probability (sometimes 100%) in patients carrying the germline mutation.
Pups were randomly designated to receive bilateral freezing lesions or sham surgery, balancing treatment within litters.
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