Words similar to lerisetron

Example sentences for: lerisetron

How can you use “lerisetron” in a sentence? Here are some example sentences to help you improve your vocabulary:

The lack of a large change in K i for both analogs makes it difficult to interpret this data since one or both of the compounds appears to be interacting differently with the binding site than lerisetron.
While Lerisetron contains no carbonyl group, the second nitrogen contained in the benzimidazole heterocycle could act as bioisostere of this functional group [ 22 ] . Orjales demonstrated the importance of the N-benzyl group by synthesizing several N1 substituted analogs of Lerisetron.
W89 is shown interacting with the aromatic benzimidazole group of lerisetron although the precise position of W89 relative to this group is not known.
Analog 1 is far less similar to lerisetron and more similar to the 5-HT 3 R antagonist granisetron.
The interaction is included in the model based on structural information obtained from the crystal structure of AChBP [ 27 ] . The region of this protein homologous to loop E and loop D of the 5-HT 3A receptor suggests a loop structure from Y140 to Y152 and a 3-residue turn containing a glycine at position 147 and the β-strand from W89 through Y93 oriented as shown in Figure 6. The orientation of lerisetron between W89 and Y142A as shown would enable the N-benzyl group to be positioned in close proximity to R91.