Words similar to leprae
Example sentences for: leprae
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The tree of SSU sequences shows the two proteobacteria ( P. stutzeri and M. loti ) at one end of the tree with cyanobacteria ( Synechococcus sp. and Synechocystis sp.) and mycobacteria ( M. leprae and M. tuberculosis ) clades branching off from a common node (Figure 4).
Both moe BR and moe Z coexist in the M. tuberculosis genome, which exhibits nitrate reductase activity, but moe BR is missing from M. leprae , which has no nitrate reductase activity.
We have previously used a similar technique to identify M. leprae genes involved in intracellular survival [ 14 ] . That is, by expressing M. leprae genes in E. coli, we were able to isolate recombinant bacteria that exhibited increased resistance to killing by murine bone-marrow derived macrophages [ 14 ] .
Rv2235 hybridized to a band in M. tuberculosis , and under low stringency conditions recognized a band in M. leprae (data not shown).
On the basis of comparison with its close relative Mycobacterium tuberculosis, M. leprae shows a pattern of genome reduction that includes both loss of large fragments and also loss of gene function through slight changes in sequence [ 41].