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Example sentences for: leprae

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The tree of SSU sequences shows the two proteobacteria ( P. stutzeri and M. loti ) at one end of the tree with cyanobacteria ( Synechococcus sp. and Synechocystis sp.) and mycobacteria ( M. leprae and M. tuberculosis ) clades branching off from a common node (Figure 4).
The genetic organization of the origin of replication has been characterized in several Gram-positive pathogens including B. subtilis , S. coelicolor , M. tuberculosis , M. avium , M. leprae , and M. smegmatis [ 8 ] . The results of our investigation on the oriC region of M. paratuberculosis show that each of the 15 primer pairs, designed from M. avium sequence data, resulted in the successful amplification and subsequent sequencing of an ~11 kb region of the M. paratuberculosis genome.
We have previously used a similar technique to identify M. leprae genes involved in intracellular survival [ 14 ] . That is, by expressing M. leprae genes in E. coli, we were able to isolate recombinant bacteria that exhibited increased resistance to killing by murine bone-marrow derived macrophages [ 14 ] .
On the basis of comparison with its close relative Mycobacterium tuberculosis, M. leprae shows a pattern of genome reduction that includes both loss of large fragments and also loss of gene function through slight changes in sequence [ 41].
Rv2235 hybridized to a band in M. tuberculosis , and under low stringency conditions recognized a band in M. leprae (data not shown).