Words similar to leiden
Example sentences for: leiden
How can you use “leiden” in a sentence? Here are some example sentences to help you improve your vocabulary:
These primers significantly advanced the rate of ERCA amplification, cutting the reaction time in half for the Factor V Leiden probe set (data not shown), resulting in a 20-minute assay.
(TNO-Prevention and Health, Leiden The Netherlands), using a monoclonal antibody specific for the ATF as the capture antibody and a polyclonal antibody directed against BPTI as the detector antibody [ 24 ] . As a standard we used either urokinase or mhATF-BPTI.
The authors felt, however, that based on their data, no definite association between the Factor V Leiden mutation and postoperative thrombosis could be made.
Formal evidence for this association came from a large population-based patient-control study, the Leiden Thrombophilia Study, which followed 474 consecutive patients of less than 70 years of age with a first episode of objectively confirmed DVT [ 9].
However, despite association of the factor V G1691A (factor V Leiden) and prothrombin (factor II) G20210A mutations with venous thromboembolism and myocardial infarction [ 10 11 ] , neither mutation is strongly associated with risk of stroke [ 12 13 14 15 16 17 18 ] . Although a study of British adults found elevated levels of serum homocysteine to be associated with an increased risk of stroke [ 19 ] , a case-control study of a common polymorphism (methylenetetrahydrofolate reductase [MTHFR] T677C) that results in increased serum homocysteine concentrations found no difference between patients with stroke and controls in either genotype or allele frequency [ 20 ] . Because antiplatelet agents with different mechanisms of action can bring about significant reductions in stroke risk, several platelet receptor genes have been tested as candidate stroke susceptibility genes [ 21 22 ] . To date, however, no compelling evidence for an association between any platelet receptor gene polymorphism and risk of stroke has been found.
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