Words similar to lectins
Example sentences for: lectins
How can you use “lectins” in a sentence? Here are some example sentences to help you improve your vocabulary:
Instead, it appeared that the initial activation of cellular competence triggered by the mitogenic lectins was amplified by the LAF activity, which became known later as IL-1, and led to the secretion of the lymphocyte-derived IL-2 and the expression of IL-2Rs [ 14 15 ] . The subsequent interaction of IL-2 with the IL-2Rs then stimulated blastic transformation and progression through G 1 and into the S phase of the cell cycle, followed by mitosis [ 16 ] . Furthermore, detailed studies indicated that successful activation of the IL-2R is a quantal (i.e.
With the isolation of the lymphocyte-derived molecule responsible for T cell Growth Factor (TCGF) activity, which came to be known as interleukin 2 (IL-2) [ 9 10 ] , and discovery of IL-2 receptors (IL-2R) [ 11 ] , it could be shown that mitogenic lectins and specific antigens triggered an initial activation event, which was analogous to the activation of cell cycle "competence" by serum-stimulated fibroblasts, and resulted in transition from the G 0 to the G 1 phase of the cell cycle [ 12 13 ] . However, just as in serum-stimulated fibroblasts, this initial activation event did not result in lymphocyte proliferation.
Another EF-hand protein has a jacalin domain found in lectins.
In 1960 Nowell first described lymphocyte activation by mitogenic lectins to result in "blastic transformation" and subsequent mitosis, which are complex cellular events that require several days to evolve [ 1 ] . More than 40 years later, we have advanced considerably in our understanding of the cellular and molecular events responsible for these phenomena.