Example sentences for: lectins

How can you use “lectins” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Instead, it appeared that the initial activation of cellular competence triggered by the mitogenic lectins was amplified by the LAF activity, which became known later as IL-1, and led to the secretion of the lymphocyte-derived IL-2 and the expression of IL-2Rs [ 14 15 ] . The subsequent interaction of IL-2 with the IL-2Rs then stimulated blastic transformation and progression through G 1 and into the S phase of the cell cycle, followed by mitosis [ 16 ] . Furthermore, detailed studies indicated that successful activation of the IL-2R is a quantal (i.e.

  • Another EF-hand protein has a jacalin domain found in lectins.

  • With the isolation of the lymphocyte-derived molecule responsible for T cell Growth Factor (TCGF) activity, which came to be known as interleukin 2 (IL-2) [ 9 10 ] , and discovery of IL-2 receptors (IL-2R) [ 11 ] , it could be shown that mitogenic lectins and specific antigens triggered an initial activation event, which was analogous to the activation of cell cycle "competence" by serum-stimulated fibroblasts, and resulted in transition from the G 0 to the G 1 phase of the cell cycle [ 12 13 ] . However, just as in serum-stimulated fibroblasts, this initial activation event did not result in lymphocyte proliferation.

  • In 1960 Nowell first described lymphocyte activation by mitogenic lectins to result in "blastic transformation" and subsequent mitosis, which are complex cellular events that require several days to evolve [ 1 ] . More than 40 years later, we have advanced considerably in our understanding of the cellular and molecular events responsible for these phenomena.


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