Words similar to least-square
Example sentences for: least-square
How can you use “least-square” in a sentence? Here are some example sentences to help you improve your vocabulary:
Phylogenetic trees were constructed by first generating a distance matrix using the PROTDIST program and the Dayhoff PAM model for amino-acid substitutions and employing this matrix for minimum evolution (least-square) tree building [ 30] using the FITCH program.
Pairwise evolutionary distances between the sequences in concatenated alignments were calculated using the Dayhoff PAM model as implemented in the PROTDIST program of the PHYLIP package [ 44 ] . A distance tree was constructed from the resulting distance matrix by using the least-square [ 46 ] method as implemented in the FITCH program of PHYLIP [ 44 ] . The maximum likelihood tree was constructed with the JTT-F model of amino acid substitutions [ 47 ] , as implemented in the ProtML program of the MOLPHY package [ 48 ] , by optimizing the least squares tree with local rearrangements.
This prediction is not supported by linear least-square regressions, which fail to detect any substantial differences in the correlation between K s and codon bias in paralogous versus orthologous genes (data not shown), suggesting that the observation of a higher K n /K s ratio in paralogous genes cannot be explained by an underestimate of synonymous divergence in paralogs.
Given the 100 genes selected, methods such as principal component analysis, partial least-square regression or composite covariate predictor can be used to further reduce the gene dimension to two or three dimensions by taking linear combinations of the gene expression levels.
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