Example sentences for: leaky

How can you use “leaky” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second, the tet-on system is sometimes leaky, meaning that at certain genomic locations there can be significant expression of the tet-on promoter in the absence of DOX [ 33].

  • The C-terminal fragment was generated by an unusual restart of translation of the fs-α 1S message at M701, presumably by leaky ribosomal scanning, and was eliminated by a M701I mutation.

  • Fs-α 1S M701I did not recover Ca 2+transients in 9 of 9 tested cells, consistent with leaky ribosomal scanning.

  • From a methodological perspective, leaky scanning could be further used as a means to control protein expression to desired levels, since restart of translation after a premature stop codon is sensitive to the number of nucleotides separating the stop and restart codons [ 39 ] . By changing the position of the restart methionine relative to the premature stop codon, it might be possible to significantly change the level of expression of the distal protein fragment and hence functional protein as a whole.

  • She described how her family sat waist-deep in water for two weeks on a leaky fishing boat to Hong Kong, how her father gave up his own ration of rice to feed his family, how they settled in Louisville, Ky., with $100 and a gold wedding ring among them.


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