Example sentences for: late-stage

How can you use “late-stage” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thanks to late-stage capitalism, the supermarket shelves sag with scores of brands in the three main paper categories.

  • Many still think so, but in recent years a late-stage hard core of Z-film specialists has developed a different view.

  • Evidence has been accumulated that TGFβ promotes late-stage tumorigenesis by stimulating angiogenesis and invasive behaviour of tumor cells, enhancing immunosuppression and supporting epithelial-mesenchymal transition of cancer cells [ 4 ] . Furthermore, TGFβ is believed to be part of a vicious circle in bone metastases as it gets released from osteoclast-degraded bone substance and subsequently stimulates PTHrP gene expression in nearby metastatic cancer cells which in turn leads to an activation of osteoclastic bone resorption [ 11 ] . Therefore, it is of great interest to understand in more detail the molecular aspects of TGFβ-mediated gene expression in metastatic breast cancer cells and to explore ways to interfere with this tumorigenic signalling.


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