Example sentences for: langerhans

How can you use “langerhans” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The following primary monoclonal antibodies were purchased from DAKO Corporation, Carpinteria, CA: CD1a Langerhans' cell (clone NA1/34), CD3 T cell (PC3/188A), CD8 suppressor /cytotoxic T cell (DK25), CD14 Monocyte (TUK4), CD68 Macrophage (KP1), HLA-ABC Antigen/ MHC class I (W6/32), IgG (A57H), IgM (R1/69), and Ki67 Proliferating cells (Ki67).

  • This sequence is the likely nuclear localization signal (NLS) for these proteins [ 15 ] , similar to the bipartite NLS found in nucleoplasmin [ 36 ] . The one exception is the Langerhans cell protein-1 (LCP1)/KIAA0737 pair, which lacks the second basic residue of the motif.

  • A full length murine cDNA representing Langerhans cell protein 1 (LCP1) was originally cloned from maturing epidermal Langerhans cells, while its human homologue KIAA0737 was cloned from human brain [ 29 ] as was a cDNA encoding TNRC9 (also known as CAGF9) [ 32 ] . Searches of the EST database confirm that all family members are expressed at the level of mRNA, and we have shown that KIAA0808 is expressed at the level of protein using a cross-reactive anti-TOX antisera (data not shown).

  • As expected, CD-1a with characteristic stellate profiles typical for Langerhans cells were readily seen in the epidermis in all pre- and post-treatment biopsy samples.

  • Advances in transplant-based therapy for type 1 diabetes mellitus [1] and a dearth of cadaveric pancreatic islets of Langerhans have focused interest on developing renewable sources of transplant-ready islet-replacement tissues.


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