Example sentences for: kxd

How can you use “kxd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 8D), but instead exhibited a diffuse distribution similar to Rab1B(N121I) and other Rabs with mutations in the N(T)KxD motif (see Fig.

  • Similar mutations in the N(T)KxD motif of other Rab proteins typically yield soluble cytoplasmic proteins.

  • To test the possibility that protein aggregates might be formed when any Rab GTPase is overexpressed with a mutation that impairs nucleotide binding, we examined the localization of four additional members of the Rab family containing amino acid substitutions in the N(T)KxD motif.

  • Therefore, pending further investigation, we cannot rule out the alternative hypothesis that mutations in the N(T)KxD motif of Rab24, combined with features in the C-terminal domain, cause Rab24 to misfold in a unique manner, attracting non-physiological protein partners that can promote aggregation and nuclear localization.

  • Therefore, it appears that although the C-terminal domain of Rab24 is required to promote its incorporation into inclusion bodies, it does so only when expressed in the context of a Rab GTPase with a mutation in the N(T)KxD nucleotide binding motif.


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