Words similar to kxd
Example sentences for: kxd
How can you use “kxd” in a sentence? Here are some example sentences to help you improve your vocabulary:
8D), but instead exhibited a diffuse distribution similar to Rab1B(N121I) and other Rabs with mutations in the N(T)KxD motif (see Fig.
Similar mutations in the N(T)KxD motif of other Rab proteins typically yield soluble cytoplasmic proteins.
To test the possibility that protein aggregates might be formed when any Rab GTPase is overexpressed with a mutation that impairs nucleotide binding, we examined the localization of four additional members of the Rab family containing amino acid substitutions in the N(T)KxD motif.
Therefore, pending further investigation, we cannot rule out the alternative hypothesis that mutations in the N(T)KxD motif of Rab24, combined with features in the C-terminal domain, cause Rab24 to misfold in a unique manner, attracting non-physiological protein partners that can promote aggregation and nuclear localization.
Therefore, it appears that although the C-terminal domain of Rab24 is required to promote its incorporation into inclusion bodies, it does so only when expressed in the context of a Rab GTPase with a mutation in the N(T)KxD nucleotide binding motif.