Words similar to knob
Example sentences for: knob
How can you use “knob” in a sentence? Here are some example sentences to help you improve your vocabulary:
The chamber consisted of three pieces: two rectangular slabs and a central knob with a depression that fits 18 by 21 mm coverslips.
"A cuss word is written on the knob of Billy Ripken's baseball bat."
(The 88 also has a separate volume knob for the woofer, so you can adjust the bass level, which would otherwise depend greatly on room placement.)
The top looks somewhat like a discus, made of hardwood with a steel knob of spike in the center and a lead rim.
Unfortunately, naive lymphocytes are not susceptible to infection with adenoviruses due to lack of detectable expression of a viral receptor, such as the coxsackie/adenovirus receptor (CAR), which is required for efficient viral attachment [ 8 9 10 ] . The CAR protein contains two extra-cellular immunoglobulin-like (Ig) domains, the first of which appears sufficient for binding to the adenoviral fiber knob protein [ 11 12 ] . Expression of either human or murine CAR in various cell lines has been shown to facilitate gene transfer by recombinant human adenoviruses [ 8 9 10 13 ] . Stable transfection of transformed murine B and T cells lines with human CAR (hCAR) lacking its cytoplasmic domain rendered them susceptible to adenoviral transfection, establishing that lymphoid cells can be permissive hosts for adenoviral transduction and demonstrating that the cytoplasmic domain of CAR is not required for viral entry [ 13 ] . More recently, mice transgenic for full length [ 14 ] or truncated hCAR [ 15 ] have been described in which adenoviral transduction of primary lymphocytes has been demonstrated.
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