Words similar to klinefelter

Example sentences for: klinefelter

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In patients who have both Klinefelter's syndrome and RAD, the diminished level of testosterone is associated with low percentages of OKT3 +and OKT8 +and with an increase of the OKT4/OKT8 ratio [ 31].
Series of subjects with gonadal dysgenesis, and isolated cases of Klinefelter's syndrome associated with rheumatic/autoimmune diseases (RAD), suggest a relation between these clinical conditions [ 2, 3].
Nine of the 13 patients had hypergonadotropic hypergonadism, five of whom had Klinefelter's syndrome (47,XXY).
In humans, before treatment with androgens, patients who have Klinefelter's syndrome but not RAD have very diminished levels of testosterone associated with high levels of IgG, IgA, IgM, IL-2, and IL-4 and with an absolute increase of CD3 +, CD4 +, and the CD4 +/CD8 +ratio [ 30].
At present, it is considered that the frequency of male patients with hypogonadism in the general male population is somewhere between 0.04 and 1% [ 23, 24] and that the most frequent genetic alteration found in these persons is that causing Klinefelter's syndrome, whose prevalence is of the order of 0.02 to 0.09% in healthy populations [ 23, 24, 25, 26] and 0.2 to 41.