Words similar to kineret
Example sentences for: kineret
How can you use “kineret” in a sentence? Here are some example sentences to help you improve your vocabulary:
IL-1 has been implicated as a pathogenic mediator in numerous inflammatory and degenerative conditions, including rheumatoid arthritis (RA) and osteoarthritis (OA) [ 1 ] . The IL-1 receptor antagonist (IL-1Ra), a naturally occurring inhibitor of the biologic actions of IL-1, has obvious therapeutic potential in such diseases [ 2 ] ; indeed recombinant human IL-1Ra (anakinra) has recently been approved for use in patients with RA as the drug Kineret™ (Amgen, Inc., Thousand Oaks, CA, USA).
This is of real interest because the clinical response to Kineret is modest and might be explained by these circumstances.
This is why in clinical application Kineret™ must be administered by daily subcutaneous injection.
These findings are relevant to the clinical use of Kineret and the possible future use of IL-1Ra gene therapy to treat joint diseases.