Example sentences for: keto

How can you use “keto” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • HBAB, a member of the human aldo keto reductase gene family, has been shown to bind bile acids with high affinity (<1 μM) and is postulated to play a similar role as 3α-hydroxysteroid dehydrogenase in human hepatocytes [ 33 ] . Expression of HBAB in McNtcp.

  • This results in keto groups remaining at some points in the chain; hydroxyl groups (–OH), formed by reduction of a keto group, at others; double bonds between some adjacent carbon atoms, resulting from removal of the hydroxyl by loss of water (dehydration); or full saturation with hydrogen atoms elsewhere, arising by ‘enoyl’ reduction of the double bond (Figure 1C).

  • The carbon chain of the polyketide would be assembled and modified progressively as the molecule moved along the protein, interacting with each domain in turn, which would select extender units, make carbon–carbon bonds, and modify keto groups as appropriate, depending on the presence or absence of domains for the three steps in the reductive cycle.

  • The citramalate pathway for conversion of pyruvate to 2-ketobutyrate involves a carbon-chain elongation mechanism that uses an initial step of condensation with acetyl-CoA, followed by rearrangement, oxidation and elimination of a carbon to produce a keto acid differing from the original substrate by the presence of an additional carbon.

  • How does a single reductive enzyme know which keto groups to modify?


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