Words similar to keratinocytes
Example sentences for: keratinocytes
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In addition, IP-10 mRNA, which is induced in a variety of cell types by interferon-γ (IFN-γ), is augmented by IL-4 in bone marrow stromal cells [ 38] and keratinocytes [ 39] but not in respiratory epithelial primary cells or cell lines [ 40].
Cytokeratin 14 expression is associated with proliferative epidermal keratinocytes at wound sites [ 24 ] . Such expression in control unwounded skin (0 day) is, as expected, very low but increased appreciably by day 2 after wounding with peak expression at day 4. Interestingly, expression of cytokeratin 14 was up-regulated in the normal epidermis and neoepidermis of SPARC-null mice relative to those of wild-type mice (Fig.
As the clot is digested by plasmin, fibroblasts replace it with cellular FN, tenascin (TN) and Coll III [ 12 13 ] . These extracellular matrix proteins are critical for migration of endothelial cells, keratinocytes and additional fibroblasts into the wound and are important for proper generation of healthy healing tissue.
S. aureus -mediated apoptosis has been reported in epithelial cells [ 16 29 30 ] , keratinocytes [ 31 ] , endothelial cells [ 32 33 ] , and osteoblasts [ 34 ] . The two global gene regulatory loci agr and sar have been demonstrated to play a role in the induction of apoptosis in epithelial cells by S. aureus [ 33 ] . Mutants in the agr or sar loci are internalized, but do not induce apoptosis [ 33 ] . Another study demonstrated induction of apoptosis in endothelial cells by staphylococcal alpha toxin [ 32 ] .
This is in agreement with the reported literature where it has been reported that IL-12 can act only on pre-stimulated cells and has little or no effect on resting lymphocytes [ 27 ] . IL-12 is a cytokine produced to some degree by B lymphocytes but mostly by phagocytic cells including monocytes, macrophages, neutrophils, epidermal cells, keratinocytes and dendritic cells which are among the first cells to encounter a foreign antigen during infection in response to bacteria, bacterial products, intracellular parasites, etc [ 2 ] . It was found that IL-12 induced directional migration of highly enriched preparations of NK cells and CD3 activated cells but not resting T cells and monocytes.
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