Example sentences for: keratinocytes

How can you use “keratinocytes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although SPARC is required for migration of dermal fibroblasts into the wound site, it is apparently not essential to the motility of keratinocytes since reepithelialization appears normal in SPARC-null mice.

  • Cultured monocytes exposed to CEES show a transient increase in TNF-alpha [ 18 ] . Similarly, cultured normal human keratinocytes exposed to CEES show a transient increase in both TNF-alpha and IL-1beta [ 19 20 ] . In contrast to the results of Arroyo et al.

  • Histology of 6 mm wound tissues showed that at day 2 after wounding the epidermis at wound edges had grown thicker in both wild-type and SPARC-null mice, indicating that proliferation of keratinocytes had began.

  • TSP-1 is a homotrimeric multidomain glycoprotein synthesized and secreted by numerous cell types, including platelets, vascular smooth muscle cells and keratinocytes [ 4 ] . Due to its interaction with a wide variety of proteins, TSP-1 has been implicated in a number of biological processes including coagulation, cell adhesion, the modulation of cell-cell and cell-matrix interactions, control of tumor growth and metastasis, and angiogenesis [ 10 ] . Inhibition of tumor cell proliferation has been achieved in vivo by systemic treatment with TSP-1 peptide mimetics [ 11 ] , but a correlation between primary tumor TSP-1 expression and poor prognosis has not been clearly established [ 12 ] . While there are reports that these molecules can originate from tumor cells [ 13 ] , the majority of reports have suggested that the major source of both TSP-1 and OPN is tumor-associated stroma [ 14 ] or infiltrating macrophages and lymphocytes [ 15 ] .

  • Interleukin-8 (IL-8) is inducible in a wide range of cells including lymphocytes, monocytes, endothelial cells, fibroblasts, hepatocytes, and keratinocytes [ 3 4 5 ] . IL-8 is also found to be constitutively expressed in several tumor tissues including bronchogenic carcinoma, non-small cell lung cancer, colorectal carcinoma, breast cancer, melanoma, prostate cancer, gastric carcinoma, and ovarian cancer.


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