Words similar to keloids
Example sentences for: keloids
How can you use “keloids” in a sentence? Here are some example sentences to help you improve your vocabulary:
In spite of numerous studies the etiology of keloid formation remains obscure [ 1 2 3 4 5 6 7 8 9 10 11 ] . However, as TGFβ1 regulates the expression and deposition of collagenous extracellular matrix (ECM) [ 12 13 14 ] it is expected that keloids develop due to aberrant responses to this cytokine.
Although myofibroblasts were not detected in vivo [ 51 ] , the propensity of keloid fibroblasts to express α-SMA in vitro and the loss of this protein upon matrix contraction (gel relaxation) do not allow one to dismiss a role for myofibroblasts in keloids.
Usually the studied keloids are at least several months old and may have had enough time for tension relaxation and loss of α-SMA.
Interestingly, keloids in some Caucasian patients were found to contain α-SMA positive fibroblasts [ 52 ] . Many of the α-SMA positive cells were spindle-shaped, which suggests that these cells experienced outside tension.
α-SMA content and apoptosis were evaluated as a function of serum, TGFβ1 and collagen type I. The observed phenotypic differences between fibroblasts grown from glabrous vs. nonglabrous tissue suggest a reason for the exclusion of keloids from specific body sites of keloid prone individuals.