Example sentences for: karyotypes

How can you use “karyotypes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Furthermore, it has been suggested that the abnormal karyotypes that result in diseases such as Down syndrome are the result of the improper dissolution of chromosome cohesion [2].

  • Most patients (61%) had unfavorable karyotypes.

  • Primarily examined through the use of G-banding cytogenetic techniques, the human and common chimpanzee karyotypes differ by only 10 euchromatic rearrangements: a telomere fusion between PTR chromosomes 12 and 13, resulting in HSA chromosome 2, and 9 pericentric inversions (HSA 1, 4, 5, 9, 12, 15, 16, 17, 18) [ 1 2 ] . The predominance of pericentric inversions between chimps and humans highlights their potential importance in the divergence of human from non-human primate species, and provides an opportunity to investigate the mechanism facilitating these rearrangements.

  • The CpG island density is also in agreement with a report of FISH karyotypes using CpG island probes [ 46] with contrasting fluorescent signal in late-replicating regions.

  • The karyotypes of humans and the African and Asian great apes are remarkably well conserved, with relatively few large-scale chromosomal changes among these species despite the considerable phenotypic and biological differences between hominoids [ 1 2 3 ] . This conservation is particularly relevant in comparisons between the human ( Homo sapiens ; HSA) and common chimpanzee ( Pan troglodytes ; PTR) genomes, for in order to completely ascertain the evolution of our own lineage it is necessary to understand what differentiates us at the genomic level from our closest relatives.


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