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Example sentences for: karyonide

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Second, we show that the heterogeneity of TAS positions within the CR-bounding multi-TAS regions are genetically determined: the pattern is not random but reproducible from karyonide to karyonide, and it is allele-specific, indicating that each TAS in these regions is dictated by its own cis -acting sequence, which we model below as a pause site for an exonuclease that resects the new MAC end before telomerase can act.
Following pair-wise mating (conjugation), each exconjugant replaces its old parental MAC with a new MAC, developed from a mitotic daughter of its genotypically new zygotic nucleus (review: [ 14 ] ). The mitotic sister of the MAC precursor (anlage) is set aside as the new diploid germline MIC, which is then heterochromatically silenced; all known gene expression is from the MAC or MAC anlage [ 15 16 17 ] . Once the anlage begins differentiation, the old MAC is apoptotically destroyed [ 18 ] . The mature exconjugant resumes feeding and establishes a vegetative clone (a karyonide) propagated by binary fission, in which the MIC replicates as a typical diploid mitotic nucleus and the MAC replicates amitotically.
A karyonide is a clone of cells established by an emerging exconjugant - that is, a clone of cells that have the same ancestral, developed new MAC [ 58 ] . If random erosion is responsible for the heterogeneity we see, then it should be different in each different karyonide.