Example sentences for: kar

How can you use “kar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, unlike most of the genes in cluster 58, KAR2 is also induced in response to heat shock, along with the other chaperone genes in cluster 11, by the transcription factor Hsf1p [ 31].

  • The clustering of KAR2 with genes in these two clusters not only reflects the functional role of the encoded protein but also corroborates the conditional regulation of KAR2 expression.

  • More than 75% (23/31) of the characterized genes within the top 50 genes in this cluster are localized to the ER and participate in various aspects of secretion, including protein folding ( KAR2, LHS1, FKB2, JEM1 ), protein disulfide isomerization ( EUG1, PDI1, ERO1 ), protein glycosylation ( GFA1, PMT3, PMI40, SEC59, WBP1, OST2 ), and forward and retrograde trafficking ( ERD2, ERP1, ERP2, SEC24, SEC13, RET2, RET3, and others [ 21]).

  • An illustration is provided by the gene KAR2 , which encodes an HSP70 protein-folding chaperone localized to the endo-plasmic reticulum (ER) that is known to respond to defects in ER secretion and to unfolded proteins in this organelle (see [ 23] for review).

  • Indirect immuno-fluorescence was performed as previously described [ 46 ] . Rabbit anti-Kar2 polyclonal antibodies [ 45 ] were used at 1:5000 and detected with Texas Red Goat-anti-Rabbit secondary antibody.


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