Example sentences for: kar

How can you use “kar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Consistent with the known functions of the protein, KAR2 has significant membership in two clusters.

  • An illustration is provided by the gene KAR2 , which encodes an HSP70 protein-folding chaperone localized to the endo-plasmic reticulum (ER) that is known to respond to defects in ER secretion and to unfolded proteins in this organelle (see [ 23] for review).

  • However, unlike most of the genes in cluster 58, KAR2 is also induced in response to heat shock, along with the other chaperone genes in cluster 11, by the transcription factor Hsf1p [ 31].

  • Consistently, most of the top genes in this group, including KAR2 , contain multiple Hsf1p-binding sites in their promoters.

  • That KAR2 clusters with both groups of genes reflects the dual role of Kar2p in the response to ER-specific challenges and to conditions that generally destabilize proteins throughout the cell, presumably without affecting other aspects of secretion.


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