Example sentences for: kar

How can you use “kar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Logarithmically growing cultures of npa1-1/sec23 and npa2-1/sec13 were shifted to the non-permissive temperature as before and then fixed and processed for IF with polyclonal antibodies against Kar2p to visualize the ER [ 45 ] . The monoclonal antibody mAb414, which recognizes a subset of Nups distinct from Nic96p and Nup170p [ 46 ] , was also used because the GFP fluorescence of the GFP-Nups was more sensitive to fixation when the GFP-Nups were mislocalized than when they remained at the nuclear rim (unpublished observation).

  • Although the localization patterns at late time points after temperature shifting were similar, the localizations of the ER protein Kar2p and the Nups were not overlapping.

  • In response to defects in ER secretion, KAR2 is known to be induced by the transcription factor Hac1p as part of the unfolded protein response (UPR) [ 25, 26, 27, 28].

  • In addition, KAR2 also has significant membership in a second cluster (cluster 11 in Figure 5d), which is composed of genes that were induced following heat shock and diamide treatment.

  • However, unlike most of the genes in cluster 58, KAR2 is also induced in response to heat shock, along with the other chaperone genes in cluster 11, by the transcription factor Hsf1p [ 31].


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