Words similar to kar

Example sentences for: kar

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That KAR2 clusters with both groups of genes reflects the dual role of Kar2p in the response to ER-specific challenges and to conditions that generally destabilize proteins throughout the cell, presumably without affecting other aspects of secretion.
However, unlike most of the genes in cluster 58, KAR2 is also induced in response to heat shock, along with the other chaperone genes in cluster 11, by the transcription factor Hsf1p [ 31].
An illustration is provided by the gene KAR2 , which encodes an HSP70 protein-folding chaperone localized to the endo-plasmic reticulum (ER) that is known to respond to defects in ER secretion and to unfolded proteins in this organelle (see [ 23] for review).
In addition, KAR2 also has significant membership in a second cluster (cluster 11 in Figure 5d), which is composed of genes that were induced following heat shock and diamide treatment.
In response to defects in ER secretion, KAR2 is known to be induced by the transcription factor Hac1p as part of the unfolded protein response (UPR) [ 25, 26, 27, 28].