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Example sentences for: kafstcxsh

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The presence of no fewer than five of the following consensus sequence signature motifs (see Figure 4) was used as a criterion for recognizing ORs: EF(I/L)LLG(L/F) (upstream of TM1), PMYFFL (TM2), MA(Y/F)DRY(V/L/A)AIC (junction of TM3 and IC2), three C (EC2), SY (junction of TM5 and IC3), KAFSTCXSH (IC3), P(M/L)LNP(L/I/F)IY (TM7).
The highly conserved motif KAFSTCXSH (X is any amino acid) in IC3 contains one of the cysteines from the intracellular pair conserved in many G-protein-coupled receptors, as well as serines and threonines potentially involved in phosphorylation events as discussed below.