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Example sentences for: kafstcxsh
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The highly conserved motif KAFSTCXSH (X is any amino acid) in IC3 contains one of the cysteines from the intracellular pair conserved in many G-protein-coupled receptors, as well as serines and threonines potentially involved in phosphorylation events as discussed below.
The presence of no fewer than five of the following consensus sequence signature motifs (see Figure 4) was used as a criterion for recognizing ORs: EF(I/L)LLG(L/F) (upstream of TM1), PMYFFL (TM2), MA(Y/F)DRY(V/L/A)AIC (junction of TM3 and IC2), three C (EC2), SY (junction of TM5 and IC3), KAFSTCXSH (IC3), P(M/L)LNP(L/I/F)IY (TM7).