Example sentences for: k-

How can you use “k-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • USAT 's "Money" section front points to a Y2K-related panic point few have discussed before now: a possible year-end-driven gas crunch that could, in the paper's words, "make lines at ATM machines and supermarket checkouts seem tame by comparison."

  • The state has spent, says the AP, millions in an effort to make its computers Y2K-compliant.

  • The cyclooxygenase pathway and NSAIDs have been implicated in pancreatic carcinogenesis, as elevated levels of COX-2 mRNA and protein have been detected in pancreatic carcinomas relative to histologically normal cells [ 14 15 16 17 18 19 ] . Further, both aspirin [ 20 21 22 ] and other NSAIDs [ 19 ] have been shown to inhibit pancreatic cancer cell proliferation and induce apoptosis in vitro . Recent studies have also reported an association between oncogenic ras and COX-2 expression [ 23 24 ] . Since pancreatic tumors tend to exhibit a high frequency of K- ras mutations [ 25 ] , the relationship between the K- ras oncogene and COX-2 should be explored further in vivo.

  • Many other associated mutation or amplification of oncogenes, tumor suppressor genes including p53, K-ras, N-ras and N-myc, etc. are frequently seen, but the roles of these gene mutations/amplifications in pathogenesis of the tumor remain largely unclear [ 4 ] ; [ 5 ] . The alveolar subtype of rhabdomyosarcoma, however, is consistently associated with two common chromosomal translocations.

  • The JNK pathway is involved in apoptosis [ 13 ] , arginine vasopressin-induced increases in smooth muscle α-actin in vascular smooth muscle cells [ 14 ] as well as in phosphorylation of transcription factors c-jun, ATF-2 and ELK-1 and phosphorylation of Na-K-2CI cotransporter [ 15 ] . The p38 pathway has been implicated in apoptosis [ 16 ] , neointimal hyperplasia after vascular injury [ 17 ] as well as angiotensin ll-induced contraction in vascular smooth muscle [ 18 ] .


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