Words similar to juxtanuclear

Example sentences for: juxtanuclear

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The observed intracellular membrane (ER) localization and proteasome inhibitor-induced juxtanuclear aggregate accumulation (aggresome) is consistent with that reported for other proteins being degraded by such a pathway [ 18 24 ] . When treated with proteasome inhibitors, overexpressed wild type α i2 also accumulates in aggresome-like structures (Figure 7), suggesting that Gα may normally be degraded by a proteasome-dependent pathway.
However, over-expression of βγ prevents ALLN-induced juxtanuclear accumulations of α i2 but not sα i2 (Figure 9).
Instead of the usual Rab1B juxtanuclear Golgi localization, the Rab1B(wt)/Rab24 chimera showed a broader cytoplasmic distribution similar to that of Rab24(wt) (Fig.
This region, commonly referred to as the hypervariable domain, plays a major role in the subcellular targeting and functional specificity of each Rab protein [ 49 ] . In accord with this view, replacement of the hypervariable domain of Rab24(wt) with the corresponding domain from Rab1B, caused the resulting chimera to exhibit a discrete juxtanuclear Golgi-like fluorescence pattern typical of Rab1B in 293 cells [ 50 51 ] . (Fig.