Words similar to jnk

Example sentences for: jnk

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In particular, we have found that Btk-deficient DT40 cells reconstituted with Txk, an atypical Tec family PTK, fail to undergo BCR-induced JNK activation (Tomlinson and Johnston, unpublished data) and apoptosis [ 13], but ERK activation is relatively normal [ 13].
Membranes were then incubated with primary antibodies to various MAPK family members overnight at 4°C (phospho-ERK, 1:5000, Promega; Madison, WI; phospho-p38, 1:1000, New England Biolabs, Beverly, MA; phospho-JNK, 1:500, Santa Cruz Biotechnology, Inc., Santa Cruz, CA).
Interestingly, JNK activity was also lower in the NIH3T3 cells expressing the tyrosine phosphorylated Cas chimera than the vector transfected cells, suggesting that this chimera also affected JNK activity in those cells (Fig.
In addition, GSTP1-1 acts as a negative regulator of JNK primarily through direct protein:protein interactions [ 9 10 ] . These data suggest that GSTP1-1 has a role in regulation of kinase activities and cell proliferation [ 8 11 12 13 ] . Because of this available background information, the HL60 wild type and TLK286 resistant cell lines were chosen as model systems for analysis by ADGE microarray.
Addition of 4-HT to cells expressing WT Btk:ER induced JNK phosphorylation to a level that was similar to that seen with anti-μ treatment (Fig 3B, lanes 2-4) or with both 4-HT and anti-μ (Fig 3B, lane 5).