Words similar to jnk

Example sentences for: jnk

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This assay was chosen to ensure that the western analyses used were sufficiently sensitive to detect changes in the activation of the JNK pathway.
Angiotensin II (10 -8- 10 -5M) produced a significant increase in the level of JNK phosphorylation (figure 5).
The MAP kinase pathway consists of 3 major parallel pathways designated as the ERK (p42/44, Extracellular signal-Regulated Kinase), SAPK/JNK (p46, Stress-Activated Protein Kinase/ c-Jun NH2-terminal Kinase) and p38 pathways [ 12 13 14 ] . Activation of each pathway above involves phosphorylation of a number of upstream and downstream family members of the pathway.
The mitogen-activated protein kinase (MAPK) family consists of three commonly recognized subgroups: the extracellular signal-regulated kinase (ERK), the c-jun-N-terminal kinase (JNK), also known as the stress activated protein kinase (SAPK) and the p38 kinase.
The JNK pathway is involved in apoptosis [ 13 ] , arginine vasopressin-induced increases in smooth muscle α-actin in vascular smooth muscle cells [ 14 ] as well as in phosphorylation of transcription factors c-jun, ATF-2 and ELK-1 and phosphorylation of Na-K-2CI cotransporter [ 15 ] . The p38 pathway has been implicated in apoptosis [ 16 ] , neointimal hyperplasia after vascular injury [ 17 ] as well as angiotensin ll-induced contraction in vascular smooth muscle [ 18 ] .