Example sentences for: jnk
How can you use “jnk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Upon 4-HT treatment, phosphorylated JNK was detected in parental cells but not in PLCγ2-deficient cells (Fig 5B, lanes 2 and 7).
In particular, we found that the tyrosine phosphorylated Cas SD domain blocked v-crk mediated activation of the JNK pathway.
Rabbit anti-phospho Erk MAPK (1:5000, Promega, Madison, Wl), rabbit anti-phospho JNK MAPK (1:5000, Promega, Madison Wl), rabbit anti-phospho p38 MAPK (1:1000, Cell Signaling, Beverly, MA), mouse anti-total Erk (1:5000, Zymed, San Francisco, CA) rabbit anti-total JNK MAPK (1:5000, Santa Cruz BioTechnologies, Santa Cruz, CA) or rabbit anti-total p38 MAPK (1:1000, Cell Signaling, Beverly, MA) were incubated with blots overnight (4°C).
Consistent with this idea, results from this study suggest that an unfavorable balance of the JNK and ERK causes the cell death observed in cholesterol oxide treated microglia.
Activation of the JNK pathway can lead to the phosphorylation of downstream members including c-jun that belongs to the AP-1 transcription factor family [ 12 52 ] . Because results from this study indicated that JNK pathway was activated by 25-OH-cholesterol, one could expect that AP-1 would be activated in cells treated with cholesterol oxides.