Example sentences for: itk

How can you use “itk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Data suggest that, for Itk, this membrane association specifically targets the protein to glycolipid enriched detergent-insoluble membrane microdomains known as "RAFTs" and that both this association and the activation of Itk requires the PH domain [ 29].

  • Data suggest that membrane association of Itk and Btk requires the interaction of their PH domains with products of PI3K, thereby facilitating phosphorylation by Src family kinases [ 27, 28].

  • Btk is the prototypical member of the Tec family of non-receptor protein tyrosine kinases (PTKs) that includes Bmx, Itk, Tec and Txk [ 2, 3].

  • This subfamily includes six members: Btk, Tec, Itk/Tsk/Emt, Bmx/Emt, Dsrc29, and Rlk/Txk [ 3, 6, 7].

  • Recent evidence from gene-targeted mice suggests that Rlk may synergize with Itk in signaling from the T cell receptor to activate phospholipase C-γ [ 20].


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