Words similar to itk

Example sentences for: itk

How can you use “itk” in a sentence? Here are some example sentences to help you improve your vocabulary:

While Rlk is phosphorylated similarly to Btk and Itk, there are marked differences between these two kinases.
Recent data argue that Itk interacts directly with Slp-76 and Grb2 to participate in a LAT-nucleated T cell signaling complex involved in PLC-γ activation [ 5, 29].
Recently, it has been found that the activation of Btk and Itk by Src family kinases is potentiated by and requires the activity of Phosphoinositide 3-kinase (PI3K), the products of which interact with the PH domains of Tec kinases [ 27, 28].
Interestingly, we also find that the full-length form of Rlk has a higher basal level of tyrosine phosphorylation and kinase activity than Itk when expressed in heterologous cells, consistent with potentially different localizations and upstream interactions (unpublished observations).
For example, in the Jurkat lymphoma cell line, which is deficient in the inositol phosphatase PTEN, Itk is constitutively associated with the membrane [ 36].