Words similar to itk

Example sentences for: itk

How can you use “itk” in a sentence? Here are some example sentences to help you improve your vocabulary:

Indeed, in Jurkat cells, which are deficient in the inositol phophatase PTEN, Itk is constitutively associated with the membrane unless the cells are treated with inhibitors of PI3K or transfected with PTEN [ 36].
Recent evidence from gene-targeted mice suggests that Rlk may synergize with Itk in signaling from the T cell receptor to activate phospholipase C-γ [ 20].
Recent data suggests that both Itk and Btk can also be associated with lipid RAFTs [ 29, 35].
It is also of note that we can reproducibly co-immunoprecipitate Rlk and Fyn, perhaps due to their association with RAFTs, whereas we have been unable to co-precipitate Itk with Src family kinases when co-expressed in 293T cells (data not shown), again demonstrating distinct properties of the Rlk protein compared to certain other members of the Btk family.
Furthermore, we have found that combined mutation of Rlk and Itk leads to profound defects in TCR signaling associated with impaired activation of PLC-γ [ 20].