Words similar to isomerase
Example sentences for: isomerase
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Feeding our diets affected various genes containing a PPRE, with roles in triacylglycerol synthesis (mitochondrial glycerol-3-phosphate acyltransferase, Gpam), FA oxidation (carnitine palmitoyl transferase, Cpt1; dienoyl CoA isomerase, Ech1), FA desaturation (stearoyl-coenzyme A desaturase, Scd1 or Δ9 desaturase), gluconeogenesis (cytosolic phosphoenolpyruvate carboxykinase 1, Pck1 or PEPCK; glucose-6-phosphatase, G6pc), cytochrome p450 metabolism (Cyp4a-10 and -14), FA transport (Cd36; FA binding protein, Fabp5), cholesterol metabolism and transport (apolipoprotein A4, Apoa4; apolipoprotein B-100, ApoB-100), and ketone body formation (mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2, Hmgcs2).
Both WU-BLAST and 123D correctly recognized the template structure 1fw1 (glutathione transferase z/maleylacetoacetate isomerase).
The hybrid-fold-recognition method, which combines sequence-profile analysis with alignment-based secondary-structure prediction [ 22] and the 3D-PSSM method [ 23] both suggested a likely α-amylase-like triosephosphate isomerase (TIM) barrel structure for this protein family.
Nostoc has frnE (encoding a thiol-disulfide isomerase) inserted between tyrA (p) and aroB . Four subclasses of tyrA are defined according to the substrate specificities of the TyrA gene product: tyrA p , specific for prephenate; tyrA a , specific for arogenate; tyrA c , accepts either prephenate or arogenate; and tyrA (p) , has broad specificity but exhibits a distinct preference for prephenate.
The first, the ER overload response, triggers the activation of the transcription factor NFkB and the subsequent upregulation of inflammatory proteins [ 13 ] . The second, the unfolded protein response (UPR) induces three divergent cellular events: (i) the activation of transcription factor ATF6 leading to the upregulation of ER chaperones such as protein disulfide isomerase, (ii) upregulation of the pro-apoptotic transcription factor GADD153 and (iii) suppression of protein synthesis via phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by pancreatic eIF2α kinase (PEK/PERK, [ 11 12 ] ). Upregulation of the ER chaperones, GADD153 and PERK in response to a toxic insult would constitute direct evidence of an ER stress response.
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