Example sentences for: isomerase

How can you use “isomerase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This is the E longation factor- I somerase (EI)-barrel found in ribosomal proteins, such as L3, GTPase translation factors, ferredoxin reductase, and L-fucose isomerase [ 62 66 ] . It seems likely that the EI-barrel and the DPBB evolved from ancient three-stranded ancestral units, which were stabilized via the formation of different barrel structures through homo-dimerization.

  • FK506-binding protein 5/FKBP51 is a co-chaperone protein that has peptidylprolyl isomerase activity and interacts with the progesterone receptor [ 25].

  • The hybrid-fold-recognition method, which combines sequence-profile analysis with alignment-based secondary-structure prediction [ 22] and the 3D-PSSM method [ 23] both suggested a likely α-amylase-like triosephosphate isomerase (TIM) barrel structure for this protein family.

  • The first, the ER overload response, triggers the activation of the transcription factor NFkB and the subsequent upregulation of inflammatory proteins [ 13 ] . The second, the unfolded protein response (UPR) induces three divergent cellular events: (i) the activation of transcription factor ATF6 leading to the upregulation of ER chaperones such as protein disulfide isomerase, (ii) upregulation of the pro-apoptotic transcription factor GADD153 and (iii) suppression of protein synthesis via phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by pancreatic eIF2α kinase (PEK/PERK, [ 11 12 ] ). Upregulation of the ER chaperones, GADD153 and PERK in response to a toxic insult would constitute direct evidence of an ER stress response.

  • Both WU-BLAST and 123D correctly recognized the template structure 1fw1 (glutathione transferase z/maleylacetoacetate isomerase).


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