Words similar to isomerase
Example sentences for: isomerase
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Nostoc has frnE (encoding a thiol-disulfide isomerase) inserted between tyrA (p) and aroB . Four subclasses of tyrA are defined according to the substrate specificities of the TyrA gene product: tyrA p , specific for prephenate; tyrA a , specific for arogenate; tyrA c , accepts either prephenate or arogenate; and tyrA (p) , has broad specificity but exhibits a distinct preference for prephenate.
The order of the microsyntenic genes was highly conserved in the three regions with the colinear pattern of three genes - phospholipase-like protein (pEARLI 4), cyclophilin-type peptidyl-prolyl cis/trans isomerase (PPI), and a cluster of SAUR and auxin-induced proteins (COSAP) - serving as a common footprint for these MSRs.
This is the E longation factor- I somerase (EI)-barrel found in ribosomal proteins, such as L3, GTPase translation factors, ferredoxin reductase, and L-fucose isomerase [ 62 66 ] . It seems likely that the EI-barrel and the DPBB evolved from ancient three-stranded ancestral units, which were stabilized via the formation of different barrel structures through homo-dimerization.
Several well-characterized plasmodial genes were identified in this metabolic collection, including P. falciparum lactate dehydrogenase (PfLDH; 027743), enolase (U00152), triose-phosphate isomerase (PfTPI; L01654), glucose-6-phosphate isomerase (PfG6PI; J05544), hypoxanthine-guanine phosphoribosyl-transferase (PfHGPRT; X16279) and dihydropteroate synthetase (PfDHPS; U07706).
The first, the ER overload response, triggers the activation of the transcription factor NFkB and the subsequent upregulation of inflammatory proteins [ 13 ] . The second, the unfolded protein response (UPR) induces three divergent cellular events: (i) the activation of transcription factor ATF6 leading to the upregulation of ER chaperones such as protein disulfide isomerase, (ii) upregulation of the pro-apoptotic transcription factor GADD153 and (iii) suppression of protein synthesis via phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) by pancreatic eIF2α kinase (PEK/PERK, [ 11 12 ] ). Upregulation of the ER chaperones, GADD153 and PERK in response to a toxic insult would constitute direct evidence of an ER stress response.
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