Words similar to islet
Example sentences for: islet
How can you use “islet” in a sentence? Here are some example sentences to help you improve your vocabulary:
βOgg1 is an alternatively spliced form of Ogg1 that contains a mitochondrial targeting signal in the C-terminal portion of the protein [ 41 ] . Specific upregulation of mitochondrial but not nuclear Ogg1 occurs during aging in rodents [ 42 ] . A specific increase of Ogg1 in islet cell mitochondria is consistent with the idea that increased β-cell mitochondrial oxidative metabolism due to hyperglycemia is a major factor behind the DNA damage.
In a summary of the 1977 Workshop on Pancreatic Islet Cell Transplantation in Diabetes, Lacy commented on the feasibility of “islet cell transplantation as a therapeutic approach [for] the possible prevention of the complications of diabetes in man” [12].
However, both GAD65 and GAD67 mRNA can be detected in the thymic medullary epithelial cells in mice [ 24 ] . Thus, despite thymic expression of GAD65 and GAD67 at the level of mRNA, NOD mice spontaneously develop autoreactivity to these islet (and brain) expressed proteins, and re-challenge of mice that have been immunized with peptides from GAD65 results in severe anaphylactic reactions.
First, our molecular analysis of differentiating IPCs showed that they remain distinct from mature pancreatic islet β-cells; in other words, the insulin + cells derived by our methods are not mature β-cells.
Current islet transplantation methods require an estimated 5 × 10 8 to 10 9 β-cells per recipient [45].
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