Example sentences for: islet

How can you use “islet” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Yet despite continued procedural improvements, only about 10% of islet recipients in the late 1990s achieved euglycemia (normal blood glucose).

  • Improvements in isolation techniques and immunosuppressive regimens ushered in the first human islet transplantation clinical trails in the mid-1980s.

  • βOgg1 is an alternatively spliced form of Ogg1 that contains a mitochondrial targeting signal in the C-terminal portion of the protein [ 41 ] . Specific upregulation of mitochondrial but not nuclear Ogg1 occurs during aging in rodents [ 42 ] . A specific increase of Ogg1 in islet cell mitochondria is consistent with the idea that increased β-cell mitochondrial oxidative metabolism due to hyperglycemia is a major factor behind the DNA damage.

  • With over 1 million Americans dealing with T1DM, it would cost over $100 billion to give each patient a single islet transplant, with little assurance as yet of any long-term benefit.

  • Just as early studies showed islet transplantation's promise, research must now overcome the hurdles revealed by the recent islet transplant experience.


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