Example sentences for: isis

How can you use “isis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Nonetheless, ISIS 15534 potently inhibits the expression of PP5 in cultured cells for ~ 48-72 hours (IC 50 of <75 nm), which affords a ~ 24-48 hour window in which the expression of PP5 is essentially ablated [ 24, 25].

  • Since PP5 is sensitive to inhibition by okadaic acid, we tested the possibility that PP5 acted at a more global level by assessing the effect of ISIS 15534 on the cellular distribution of NFAT-GFP.

  • To further characterize the mechanism by which PP5 affects GR function, in the present study we employed a GR-GFP fusion protein and fluorescent microscopy to follow the movement of GR in cells treated with dexamethasone and ISIS 15534.

  • Stably-transfected HeLa cells expressing GFP-NFAT [ 38] were grown on glass coverslips to approximately 30% confluency and either left untreated or treated with, ISIS 15534, or ISIS 15521 (a mismatched oligonucleotide control for ISIS 15534) in the absence of serum as described above.

  • Nuclear accumulation of GR-GFP was also observed when the expression of PP5 was suppressed by treatment with ISIS 15534 after ~ 24 hours.


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