Example sentences for: isis

How can you use “isis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In contrast, mobility gel-shift analysis revealed that treatment with ISIS 15534 produces a marked increase in the association of GR with GRE-containing DNA, and transient transfection studies employing a GR-responsive reporter plasmid revealed that the suppression of PP5 expression activates GR-dependent transcription in the absence of hormone [ 25].

  • ISIS 15534 promotes nuclear localization of GR

  • Vitravene, from Isis Pharmaceuticals in Carlsbad, California, is used to treat cytomegalovirus infections in the eye for patients with HIV.

  • In contrast, following treatment with ISIS 15534, GR-GFP was localized in the nucleus without dexamethasone treatment.

  • Therefore, the previously reported increase in GR-induced transcriptional activity that occurs after ISIS 15534 induced suppression of PP5 expression likely results from the nuclear accumulation of GR in a form that is capable of binding DNA yet still requires agonist to elicit maximal transcriptional activation.


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