Words similar to irs-
Example sentences for: irs-
How can you use “irs-” in a sentence? Here are some example sentences to help you improve your vocabulary:
The second class of phosphotyrosine dependent adaptors exemplified by proteins such as Cas, Dok, IRS-1 and 2 or Slp-76, as cytosolic adaptors, or LAT, TRIM or SIT as membrane anchored adaptors, also require the activation of upstream signals by tyrosine kinases for their function.
Infection with the MK virus eliminated the IGF-I stimulated phosphorylation of IRS-1 confirming that the expressed receptor was acting as a dominant negative to inhibit the endogenous receptors.
To test the function of the virally encoded receptors, we measured IGF-I stimulated autophosphorylation of the IGF-IR and phosphorylation of IRS-1.
Infection with the WT virus leads to a large increase in IGF-IR and IRS-1 tyrosine phosphorylation.
Phosphorylation IRS-1 was evident in the LacZ infected cells but little IGF-IR phosphorylation was seen as the cells express few receptors (Figure 4).
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