Words similar to irs-

Example sentences for: irs-

How can you use “irs-” in a sentence? Here are some example sentences to help you improve your vocabulary:

The second class of phosphotyrosine dependent adaptors exemplified by proteins such as Cas, Dok, IRS-1 and 2 or Slp-76, as cytosolic adaptors, or LAT, TRIM or SIT as membrane anchored adaptors, also require the activation of upstream signals by tyrosine kinases for their function.
Infection with the WT virus leads to a large increase in IGF-IR and IRS-1 tyrosine phosphorylation.
Infection with the MK virus eliminated the IGF-I stimulated phosphorylation of IRS-1 confirming that the expressed receptor was acting as a dominant negative to inhibit the endogenous receptors.
To test the function of the virally encoded receptors, we measured IGF-I stimulated autophosphorylation of the IGF-IR and phosphorylation of IRS-1.
Adaptor proteins that regulate tyrosine kinase signaling pathways fall into two major categories, those primarily with protein/protein interaction domains such as SH2, SH3, PTB, and PH domains, exemplified by the adaptor proteins c-crk, nck and grb-2, and those that are primarily tyrosine phosphorylated, exemplified by proteins such as Cas, Dok, IRS-1 and 2, Slp-76, LAT, TRIM or SIT.