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Example sentences for: involved
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Two secreted proteins or protein complexes are involved in sensing cell density [ 5 ] . Prestarvation factor (PSF) is a glycoprotein that is secreted when cells are growing and accumulates as an indicator of the ratio of cell density relative to the supply of food [ 6 7 ] . When the ratio of Dictyostelium cells to nutrients is above a certain threshold, PSF induces the expression of several early developmental genes including discoidin I, lysosomal enzymes, and some components of the cAMP pulsing system [ 8 9 ] . Once nutrients are depleted, PSF production declines and a second cell density-sensing pathway is activated.
The coiled-coil motif has also been identified in a variety of proteins associated with centromeres, centrosomes, the nuclear matrix, and chromatin [ 10 11 12 13 14 ] . TPR, a protein associated with the inner filaments of the nuclear pore complex is an extended coiled-coil protein [ 15 ] . The filamentous structures associated with both the outer and inner surface of the nuclear pore complex suggest that additional unknown coiled-coil proteins might be involved in its assembly.
This calendar was used during the interview to help them remember what they were doing during different periods of their lives and whether drinking alcohol was involved.
As more researchers in genetics and neuroscience have become involved, Amaral says, the tensions between the parent groups and the National Institutes of Health have eased.
These candidate genes will make it possible to study not only polymorphisms associated with a hypercoagulable state, but also to study the genes involved in pathways that may lead to the development of vasculopathy (genes involved in endothelial cell function, inflammation, and adhesion, platelet activation and responsiveness).
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