Example sentences for: invariant

How can you use “invariant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 2) can be identified, which are strictly invariant among all the yCCR4-related proteins, but have no equivalent in the presently aligned AP-endonucleases and DNAseI, or in other Mg 2+-dependent endonuclease fold-containing proteins previously described (not shown) [ 12 13 ] . These CCR4-specific amino acids are most probably relevant to functions common to and specific for all yCCR4-related proteins (see Discussion).

  • The sequence in this NH 2 extension is highly conserved, with 46% of the residues invariant among midasins from the available organisms.

  • Both lowess and invariant set normalization methods resulted in similar array distributions, whereas our version of lowess normalization gave more comparable distributions than the Raffy version.

  • The ability of a MIDAS protein to bind its protein ligand is tightly linked with the presence of intact MIDAS motifs: mutations to the metal-coordinating residues in these motifs, weaken or eliminate ligand binding [ 35 36 ] . An additional set of MIDAS-like proteins, that includes the integrin β-chain [ 37 38 ] and the von Willebrand Factor A domain [ 27 ] , lacks one of the three motifs and appears to bind ligands in a somewhat different manner [ 27 39 40 ] . In midasin, the presence of all three MIDAS motifs in the M-domain, with the putative metal ion-binding residues in the motifs invariant in the available organisms, indicates that midasin belongs to the family of MIDAS-containing proteins.

  • The statistical problem is to test the hypotheses that patterns of dinucleotide over- and under-representation in a given genome are invariant.


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