Example sentences for: intranasal

How can you use “intranasal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have recently shown that mice that are exposed thrice at weekly intervals to intranasal colonization with encapsulated pneumococci are protected against subsequent carriage, that this protection is effective for heterologous as well as homologous capsular types, and that it is effective even in MuMT mice, which lack the ability to produce antibodies (Malley R, Trzcinski K, Srivastava A, Thompson CM, Anderson PW, et al.

  • We have also shown that intranasal immunization with unencapsulated, killed pneumococci protects against nasopharyngeal colonization, in a fashion that is independent of antibody but requires CD4+ T cells at the time of challenge.

  • Multiple studies have demonstrated that particle bombardment of skin elicits immune responses in larger animals [ 14 15 16 17 18 ] . Similarly, high-volume jet injection (100 μl) of either 50 or 250 μg DNA into the skin of primates induces immunity [ 19 ] . Delivery to the oral mucosa by jet injection elicited a higher IgA response than intranasal delivery in mice [ 20 ] . However, none of these studies compared different intracutaneous DNA delivery methods within the same study.


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