Example sentences for: intra-patient

How can you use “intra-patient” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The above findings suggested that both intra-patient variability (tissue heterogeneity) and inter-patient variability (polymorphic noise) had major effects on the expression profiles.

  • We conclude that intra-patient tissue heterogeneity is a major source of experimental variability in expression profiling, and must be considered in experimental design.

  • To analyze the impact of intra-patient variability (tissue heterogeneity), inter-patient variability (polymorphic noise in outbred populations), and the effect of sample mixing on the sensitivity of detection of gene expression differences between patient groups, we conducted a series of individual and mixed profiling (Table 1).

  • We have recently reported generation of expression profiling results using mixed patient samples [ 23 ] . Our hypothesis was that mixing of RNA samples from multiple regions of muscle biopsies, and from multiple patients matched for most variables (disease, age, sex), would effectively normalize both intra-patient variability (tissue heterogeneity), and inter-patient variability (SNP noise; e.g. normal human polymorphic variation unrelated to the primary defect).

  • Importantly, the variation caused by intra-patient tissue variation often overshadowed all other variables.


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