Words similar to intra-patient
Example sentences for: intra-patient
How can you use “intra-patient” in a sentence? Here are some example sentences to help you improve your vocabulary:
This data suggests that tissue heterogeneity (intra-patient variability) can be a major source of variation in expression profiling experiments, even when using relatively large pieces (50 mg) of relatively homogeneous tissues (such as muscle).
intra-patient variability [different regions of biopsy], versus diagnosis [DMD vs control], versus inter-patient variability [DMD patients in same age group], versus age of patient).
On the other hand, tissue heterogeneity (intra-patient variation; Average R 2for 10 patients = 0.92 [0.
We have recently reported generation of expression profiling results using mixed patient samples [ 23 ] . Our hypothesis was that mixing of RNA samples from multiple regions of muscle biopsies, and from multiple patients matched for most variables (disease, age, sex), would effectively normalize both intra-patient variability (tissue heterogeneity), and inter-patient variability (SNP noise; e.g. normal human polymorphic variation unrelated to the primary defect).
We conclude that intra-patient tissue heterogeneity is a major source of experimental variability in expression profiling, and must be considered in experimental design.
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