Example sentences for: interstitium

How can you use “interstitium” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • EP2 expression in uterus, vasculature and the kidney suggests that this receptor may play important roles in the functions of reproductive system, vascular tissues and interstitium of the kidney.

  • Surface epithelia of ovaries consisted of cuboidal cells; a definitive basal lamina (which eventually supports and separates surface cells from the ovarian cortical interstitium) was not readily discernible.

  • Interestingly, our study shows that tubular epithelial apoptosis was associated with TED and IF in human DNP, while normal appearance of tubular epithelium and interstitium was associated with baseline apoptosis rates in diabetic mouse models.

  • Cumulatively, however, these observations do suggest a mechanism whereby HIV-1 expression in renal epithelium may induce cyclin D 1 : activation of Src-family kinases by Nef would be expected to up-regulate cyclin D 1 gene expression and promote the synthesis and stabilization of cyclin D 1 protein via Src-Ras-MAPK and Src-PI3K-mTOR signal transduction pathways, respectively [ 32 33 34 ] . Interestingly, our unpublished in vitro observations and published data showing marked expression of basic fibroblast growth factor in the interstitium of HIVAN kidneys [ 35 ] suggest that soluble mitogens may be important cofactors with HIV-1 expression to induce cyclin D 1 . Thus, interrupting HIV-1 gene expression should down-regulate cyclin D 1 and correct the phenotypic abnormalities in infected podocytes.

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