Example sentences for: internalization

How can you use “internalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • More recently, in vitro studies carried out on δ-opioid receptors, showed that following a rapid internalization in response to an agonist stimulation, the endocytosed receptors were recycled back to the plasma membrane ( 33).

  • Our findings demonstrate that dermenkephalin, after in vivo administration, can induce an internalization of the δ-opioid receptor at the level of the spinal cord.

  • To determine the effect of the ribozyme on the functional activity of M6P/IGF2R, the binding and internalization of exogenous 125I-IGF-II was measured in cells infected with Ad-GFP/Rz-IGF2R or Ad-GFP.

  • By contrast, application of dermenkephalin induced an internalization of the δ-opioid receptor within 30 minutes.

  • These findings raise two related questions: 1) can δ-opioid receptors be internalized in vivo by the same agonist-induced endocytosis observed in vitro ? and if this is the case, 2) does the internalization process have the same kinetics reported from in vitro studies?


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