Example sentences for: internalization

How can you use “internalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The authors suggest that morphine has low intrinsic activity at μ-opioid receptor compared for instance to the lower affinity μ agonist [D-Ala 2,N-MePhe 4,Gly 5-ol]enkephaline (DAMGO) which is able to trigger an internalization process.

  • without dermenkephalin) in NaCl for 15 and 30 minutes to check if the endogenous enkephalins protected by kelatorphan and thiorphan could, by themselves, induce receptor internalization.

  • These results bring an important confirmation that data obtained in an in vitro system for G protein-coupled receptor internalization ( 3) are relevant to the CNS in vivo . The consequences on receptor expression (recycling and/or degradation) remain to be established.

  • To determine the effect of the ribozyme on the functional activity of M6P/IGF2R, the binding and internalization of exogenous 125I-IGF-II was measured in cells infected with Ad-GFP/Rz-IGF2R or Ad-GFP.

  • Our findings demonstrate that dermenkephalin, after in vivo administration, can induce an internalization of the δ-opioid receptor at the level of the spinal cord.


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