Words similar to intermediates
Example sentences for: intermediates
How can you use “intermediates” in a sentence? Here are some example sentences to help you improve your vocabulary:
There are two homologous type IA topoisomerases present in E. coli . Topoisomerase III has potent DNA decatenating activity for resolution of plasmid DNA replication intermediates, but much weaker relaxation activity than topoisomerase I [ 17 ] . To exhibit maximal relaxation activity, topoisomerase III requires high temperature (52°C) along with low magnesium and monovalent ion [ 17 18 ] . In contrast, E. coli topoisomerase I was not active in the in vitro assay for resolution of plasmid DNA replication intermediates [ 19 ] . Removal of the C-terminal 49 amino acids from the 653 amino acid topoisomerase III protein resulted in drastic reduction of catalytic activity [ 20 ] . Fusion of the carboxyl-terminal 312 amino acid residues of E. coli topoisomerase I, which includes the entire ZD domain, onto the 605 N-terminal amino acids of topoisomerase III generated a hybrid topoisomerase that has relaxation activity resembling topoisomerase III along with weak decatenating activity [ 21 ] . Although preferring single-stranded DNA as binding substrate, topoisomerase I had been shown to also bind double-stranded DNA [ 22 ] , but there is no data available to indicate which domain in the enzyme is responsible for this interaction.
Thus, it is tempting to speculate that IL-1 antagonizes the effects of TGF-β by blocking expression of essential signaling intermediates, such as SMAD4.
The major change that had to be made to the FlyBase controlled vocabulary to support this project was to name the developmental intermediates that arise during embryogenesis, that is anlagen, primordia, and anlagen in statu nascendi.
However, earlier work clearly shows that both DHA and AA can be retroconverted to 2 carbon shortened intermediates.
The proteasome assembly intermediates could be a site for the entry of substrates into the degradation chamber via an unfold-trap mechanism that is coupled to the final maturation of the 20S proteasome.
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