Words similar to intensity-dependent
Example sentences for: intensity-dependent
How can you use “intensity-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:
Experimental artifacts in microarray data are intensity-dependent and tend to occur primarily for weak spots [ 16 ] . The nucleporin 88 kD (AA488609) with the largest standard deviation in the Table 2had weak signal.
Locally weighted linear regression (lowess) [ 6] has been proposed as a normalization method for microarray assays [ 7, 8] that can remove intensity-dependent dye-specific effects in the log 2 (ratio) values.
More careful analysis of the distribution of ratios as a function of intensity suggests that an intensity-dependent assessment of local SD of the distribution provides a better measure of statistically significant differential expression; essentially calculating a local Z -score.
Then, intensity-dependent SDs on the log 2 (ratio) were computed for each array, as described in the Intensity-dependent estimation of differential expression section.
While global normalization of the data can help to provide meaningful expression ratios, a more sophisticated normalization using lowess allows for correction of intensity-dependent artifacts in the data.
Loading...