Example sentences for: insulin-treated

How can you use “insulin-treated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The total amount of p44/42 MAPK was equal and remained level in control and insulin-treated cells at all time-points (Fig.

  • In cultured human muscle cells, only the PI 3-kinase - p70 S6 kinase pathway, and not the MAPK pathway, mediates insulin up-regulation of p85α PI 3-kinase gene expression [ 26 ] . Similarly, in L6 myotubes, insulin induces hexokinase II gene transcription via the rapamycin-sensitive PI 3-kinase pathway, but not via the MAPK pathway [ 27 ] . The PI 3-kinase - p70 S6 kinase pathway, but not the MAPK pathway, mediates insulin induction of glucose-6-phosphate dehydrogenase gene expression in primary rat hepatocytes [ 28 ] . In H411E liver cells, insulin down-regulates cAMP-induced phosphoenolpyruvate carboxykinase gene transcription via the PI 3-kinase pathway, but not via the MAPK pathway [ 29 ] . Phosphorylated p70 S6 kinase has been shown to be present in the nucleus in insulin-treated cells [ 30 ] . Moreover, it has been shown that p70 S6 kinase phosphorylates and activates members of the cAMP response element modulator family of transcription factors [ 31 ] . These data raise the possibility that transcriptional regulation of SP-A gene expression occurs via the PI 3-kinase - p70 S6 kinase pathway.

  • The intensity of the immunoreactive bands of phospho-p44/42 MAPK from insulin-treated cells was 0.92 ± 0.10 relative to controls, which were made equal to one (data are the mean of two experiments performed in duplicate plus or minus the standard deviation of the mean).

  • Rapamycin also down regulated the Thr421/Ser424 phosphorylation in p70 S6 kinase in control and insulin-treated cells at both time-points (Fig.

  • The total amount of p70 S6 kinase present in the cells decreased during the 16 hour incubation period, however, there was no difference in the amount present in control vs. insulin-treated cells at any time-point (Fig.


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