Example sentences for: inside-out

How can you use “inside-out” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Single channel current recordings were carried out by the cell-attached and inside-out configurations.

  • Integrin-mediated interactions are vital to the maintenance of normal cell functioning because of their ability to mediate inside-out (intracellular to extracellular) and outside-in (extracellular to intracellular) signaling.

  • The inside-out signaling protects the host from excessive integrin-mediated cell adhesion, which could, for example, lead to spontaneous aggregation of blood cells and have profound pathological consequences.

  • Mutational studies provided the initial hints that disruption of the non-covalent clasp between α and β cytoplasmic tails is clearly the event within the structure of the integrin that initiates inside-out signaling.

  • Upon the inside-out activation, integrins bind to specific extracellular matrix proteins.


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