Example sentences for: inositol

How can you use “inositol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • GPLD1 selectively hydrolyzes inositol phosphate linkages in vitro, releasing the protein bound to the plasma membrane via a glycosylphosphatidylinositol anchor into the cytosol [ 35 ] . P24 is a neuron specific membrane protein localized in intracellular organelles of highly differentiated neural cells and is involved in neural organelle transport.

  • Members of the DNase 1, LINE-1 repeats, inositol 5'-polyphosphate phosphatase, Nocturnin, CCR4, cytolethal distending toxin, neutral sphingomyelin phosphodiesterase, and amino acid methyltransferase families were found with expectation values of 10 -4or less to be significantly similar to APE1.

  • Indeed, in Jurkat cells, which are deficient in the inositol phophatase PTEN, Itk is constitutively associated with the membrane unless the cells are treated with inhibitors of PI3K or transfected with PTEN [ 36].

  • Similarly, inositol 1,4,5-trisphosphate receptors (IP3R) are intracellular calcium release channels involved in diverse signaling pathways and are required for the activation of T lymphocytes [ 33 ] . Tat (also implicated as a neurotoxin) has been shown to release calcium from inositol 1,4, 5-trisphosphate (IP3) receptor-regulated stores in neurons and astrocytes causing premature apoptosis [ 34 ] . Down-regulation of IP3 may therefore contribute to viral latency and maintenance of an anti-apoptotic state in cells.

  • RGS3 was found to profoundly inhibit GnRH-stimulated LH secretion and 3H-inositol phosphate accumulation.


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