Example sentences for: inositol

How can you use “inositol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The SH2 domain-containing inositol phosphatase (SHIP) downregulates Btk by dephosphorylating PIP3 [ 4, 5, 6].

  • Previously, we showed that RSG3 was expressed endogenously in rat pituitary cells and, when experimentally co-expressed together with GnRH receptors in a heterologous cell line (COS1), it suppressed GnRH-stimulated inositol trisphosphate production [ 9 ] . Here, those studies have been extended to include GnRH-stimulated LH secretion using adenovirus-mediated gene transfer of RGS3 complementary DNA into normal rat pituitary gonadotropes.

  • The APEs, DNase-1 and inositol 5'-polyphosphate phosphatases (IPP) have been grouped according to the SCOP database [ 30 ] as the DNase-1 like superfamily.

  • Similarly, inositol 1,4,5-trisphosphate receptors (IP3R) are intracellular calcium release channels involved in diverse signaling pathways and are required for the activation of T lymphocytes [ 33 ] . Tat (also implicated as a neurotoxin) has been shown to release calcium from inositol 1,4, 5-trisphosphate (IP3) receptor-regulated stores in neurons and astrocytes causing premature apoptosis [ 34 ] . Down-regulation of IP3 may therefore contribute to viral latency and maintenance of an anti-apoptotic state in cells.

  • GPLD1 selectively hydrolyzes inositol phosphate linkages in vitro, releasing the protein bound to the plasma membrane via a glycosylphosphatidylinositol anchor into the cytosol [ 35 ] . P24 is a neuron specific membrane protein localized in intracellular organelles of highly differentiated neural cells and is involved in neural organelle transport.


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