Example sentences for: inositol

How can you use “inositol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • C2 domains bind a variety of substrates, such as Ca 2+, phospholipids, inositol polyphosphates and other proteins, but apparently not RNA [ 35].

  • CMV has been shown to cause calcium flow and protein kinase C (PKC) activation that could then be involved in the early activation of transcription factors [ 71 ] . Cellular levels of secondary messengers inositol 1,4,5-triphosphate and 1,2-diacylglycerol [ 71 72 73 ] , as well as the MAP kinases (ERK1 and ERK2) [ 74 75 ] are also known to be upregulated, which may have an effect on EBV reactivation.

  • The SH2 domain-containing inositol phosphatase (SHIP) downregulates Btk by dephosphorylating PIP3 [ 4, 5, 6].

  • The APEs, DNase-1 and inositol 5'-polyphosphate phosphatases (IPP) have been grouped according to the SCOP database [ 30 ] as the DNase-1 like superfamily.

  • thapsigargin and ryanodine) deplete the ER calcium pool either by (i) inhibiting the ER calcium pump and thereby preventing the replenishment of the ER calcium pool or (ii) triggering ER (ryanodine or inositol 1,4,5-trisphosphate (IP 3 ) activated) calcium release channels [ 9 ] . These phenomena can be visualized by fluorescence microscopy as a transient increase in cytoplasmic calcium concentrations (for example see [ 10 ] ). Nominally calcium-free media are used so that the effect can be distinguished from calcium influx mediated via plasma membrane channels.


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