Example sentences for: inositol

How can you use “inositol” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • IL-2-suppressed genes include lymphocyte antigen 9, inositol 1,4,5-trisphosphate 3-kinase B, and cdc25B, as well as transcriptional regulators MAX-interacting protein 1, CBP/p300-interacting transactivator, inhibitor of DNA binding 3 (Id3), glucocorticoid-induced leucine zipper (GILZ), and zinc finger protein 36/ERF-2.

  • With respect to the G protein as a locus for modulation of GnRH receptor signaling, we reported earlier that experimental expression of RGS3 but not RGS1, 2, or 4 in GnRH receptor expressing COS-1 cells suppressed GnRH-stimulated IP 3 production [ 9 ] . In the current report, we present evidence strengthening the hypothesis of a regulatory role for RGS3 in GnRH receptor signaling: adenovirus-mediated expression of RGS3 in normal pituitary gonadotropes profoundly inhibited GnRH-stimulated LH secretion and 3H-inositol phosphate accumulation.

  • thapsigargin and ryanodine) deplete the ER calcium pool either by (i) inhibiting the ER calcium pump and thereby preventing the replenishment of the ER calcium pool or (ii) triggering ER (ryanodine or inositol 1,4,5-trisphosphate (IP 3 ) activated) calcium release channels [ 9 ] . These phenomena can be visualized by fluorescence microscopy as a transient increase in cytoplasmic calcium concentrations (for example see [ 10 ] ). Nominally calcium-free media are used so that the effect can be distinguished from calcium influx mediated via plasma membrane channels.

  • CMV has been shown to cause calcium flow and protein kinase C (PKC) activation that could then be involved in the early activation of transcription factors [ 71 ] . Cellular levels of secondary messengers inositol 1,4,5-triphosphate and 1,2-diacylglycerol [ 71 72 73 ] , as well as the MAP kinases (ERK1 and ERK2) [ 74 75 ] are also known to be upregulated, which may have an effect on EBV reactivation.

  • When transfected into Chinese hamster ovary (CHO) cells, activation of the SPR results in an increase in intracellular Ca ++[ 5], accumulation of inositol phosphates and cAMP formation [ 6].


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