Example sentences for: innervate

How can you use “innervate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our previous studies reported the anatomical localization for MIF only in the bladder, while the location of MIF in the peripheral ganglia (MPG; DRG) and in the lumbosacral spinal cord was not determined since the focus was on the change in MIF amounts in these tissues following bladder inflammation [ 10 11 ] . Therefore, as part of our ongoing investigations on the role of MIF in pelvic viscera inflammation, we investigated the location of MIF in two pelvic organs (bladder and prostate) and in peripheral ganglia that innervate these viscera using immunohistochemistry.

  • Results in the present study revealed the location of MIF protein in the bladder and prostate of the rat and in the central and peripheral nervous system tissues that innervate these organs.

  • It has been shown by others that compared to muscles in the cat hindlimb where spindle classification can be based almost entirely on conduction velocity, non-limb muscles contain primary and secondary muscle spindle afferents that are generally slower conducting and exhibit overlapping bimodal or unimodal conduction velocity spectra [ 12 13 ] . These studies have shown that only the very fastest afferents innervate primary endings (>75 m/s) and the negatively adapting discharge frequency during static hold and the abrupt decrease in firing at the end of static stretch are the best criteria for characterization of primary spindle afferents.

  • Although cytokines are traditionally associated with peripheral immune reactions as part of the innate response, evidence is accumulating that they may also be involved in normal brain function and may mediate pathological responses such as hyperalgesia [ 26 27 ] . In fact, the abundance of MIF in glia of the spinal cord is particularly interesting since glial cells have been suggested as involved in hyperalgesia through the release of cytokines and other substances [ 28 ] . Given the presence of MIF in the pelvic organs (bladder, prostate) and the central and peripheral nervous system tissues that innervate these organs, as well as the fact that bladder inflammation appears to upregulate MIF in these areas, it is possible that MIF represents a therapeutic target in reducing or preventing pelvic viscera inflammation.

  • The lumbar sympathetic chain contains a large proportion of the sympathetic post-ganglionic neurons that innervate the bladder while the inferior mesenteric ganglion provides a much smaller contribution [ 12 ] . Although not directly tested in the present experiment, it is possible that some of the post-ganglionic neurons that also stained with MIF innervate the bladder and/or other pelvic viscera.


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