Words similar to innervate
Example sentences for: innervate
How can you use “innervate” in a sentence? Here are some example sentences to help you improve your vocabulary:
These neurons directly innervate the preganglionic neurons in the sacral parasympathetic nucleus that supply the excitatory impulses to the bladder and are among the first neurons in the brain to be labeled from the spinal cord.
Although cytokines are traditionally associated with peripheral immune reactions as part of the innate response, evidence is accumulating that they may also be involved in normal brain function and may mediate pathological responses such as hyperalgesia [ 26 27 ] . In fact, the abundance of MIF in glia of the spinal cord is particularly interesting since glial cells have been suggested as involved in hyperalgesia through the release of cytokines and other substances [ 28 ] . Given the presence of MIF in the pelvic organs (bladder, prostate) and the central and peripheral nervous system tissues that innervate these organs, as well as the fact that bladder inflammation appears to upregulate MIF in these areas, it is possible that MIF represents a therapeutic target in reducing or preventing pelvic viscera inflammation.
We undertook this study to answer questions not previously addressed by other investigations, namely: (1) Are the lumbosacral parasympathetic and sympathetic preganglionic neurons that innervate the bladder different from those that innervate the prostate, or to what extent do they dually innervate these organs?
Acute bladder inflammation induced by local (intravesical) administration of chemical irritants or lipopolysaccharide altered the levels of this cytokine in the bladder suggesting that MIF may be implicated in the early stages of bladder inflammation [ 10 11 ] . In addition, there were changes in the levels of MIF and cyclooxygenase-2 in the central and peripheral nervous tissues that innervate the bladder and other pelvic viscera.
Our previous studies reported the anatomical localization for MIF only in the bladder, while the location of MIF in the peripheral ganglia (MPG; DRG) and in the lumbosacral spinal cord was not determined since the focus was on the change in MIF amounts in these tissues following bladder inflammation [ 10 11 ] . Therefore, as part of our ongoing investigations on the role of MIF in pelvic viscera inflammation, we investigated the location of MIF in two pelvic organs (bladder and prostate) and in peripheral ganglia that innervate these viscera using immunohistochemistry.
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