Words similar to injury-regulated

Example sentences for: injury-regulated

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Potential roles of injury-regulated genes
Table 4 (see additional file 3) indicates the pattern of expression, class, action, and functional role for 15 previously uncharacterized, and 9 novel injury-regulated genes, amongst the 24 validated genes.
Several of these changes are maladaptive in the sense that they contribute to the generation of the abnormal sensations that constitute neuropathic pain, by producing ectopic spontaneous activity into the CNS, altering synaptic drive, increasing excitability and diminishing inhibitory action in the dorsal horn of the spinal cord, and by making novel synaptic contacts with inappropriate neurons [ 1 4 ] . A number of the injury-regulated genes we describe here may contribute directly to this altered sensory processing; CB1 receptor, VGF, the phospholemman ion channel, SNAP25 A, endothelin-1 and the ligand-gated 5-HT3 receptor (Table 4, see additional file 3).