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Example sentences for: influenzae
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The sequences of the proteins encoded in complete genomes were extracted from the Genome division of the Entrez retrieval system [ 34 ] . The analyzed genomes included those of 30 bacteria: Aquifex aeolicus (Aquae), Bacillus halodurans (Bacha), Bacillus subtilis (Bacsu), Borrelia burgdorferi (Borbu), Buchnera sp. (Bucsp), Campylobacter jejunii (Camje), Caulobacter crescentus (Caucr), Chlamydia trachomatis (Chltr), Chlamydophila pneumoniae (Chlpn), Deinococcus radiodurans (Deira), Escherichia coli (Escco), Haemophilus influenzae (Haein), Helicobacter pylori (Helpy), Lactococcus lactis (Lacla), Mesorhizobium loti (Meslo), Mycoplasma genitalium (Mycge), Mycoplasma pneumoniae (Mycpn), Mycobacterium tuberculosis (Myctu),
In view of the mounting evidence that nontypeable H. influenzae grows as a biofilm in otitis media with effusion and in the respiratory tract of adults with COPD, it will be important to characterize the bacterial surface antigens of the organism during growth as a biofilm.
The apparent goodness-of-fit actually gets better as window size decreases as illustrated in Figure 2for three indicated window sizes on the Haemophilus influenzae sequence.
We start however with the understanding that the sequence is fundamentally nonstationary, exhibiting statistically significant variations in base frequencies between non-overlapping windows [ 1 2 ] . Locally or globally estimated Markov models may describe it better than assuming that the bases are independent and identically distributed [ 19 ] but they fail to reflect the salient features of natural sequences [ 20 ] . For example, Robin and Daudin [ 21 ] compared the frequency of a specific motif in the genome sequence of Haemophilus influenzae to Markovian predictions and found that the observed frequencies were everywhere higher than predicted.
Nontypeable Haemophilus influenzae is an important human respiratory tract pathogen [ 1 2 3 4 ] . The bacterium causes acute otitis media as established by pure culture of the organism from middle ear fluid during disease [ 5 6 7 8 9 ] . In addition, nontypeable H. influenzae has been implicated as a cause of otitis media with effusion, which refers to the presence of fluid in the middle ear in the absence of acute symptoms.
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