Words similar to infiltrating
Example sentences for: infiltrating
How can you use “infiltrating” in a sentence? Here are some example sentences to help you improve your vocabulary:
In immune competent mice, intratumoral injection of SLC/CCL21 led to a significant increase in CD4 and CD8 T lymphocytes as well as DC infiltrating the tumor and the draining lymph nodes.
As the White House, FBI, and CIA became increasingly involved in clandestine, invasive, and illegal acts against citizens--bugging, wiretapping, surveillance, opening mail, infiltrating organizations--the government claimed it was just protecting the public from radicals, but people soon stopped buying the explanation.
Sixty-eight frozen human breast tissue specimens were evaluated by LCM, qPCR and IHC, including 31 primary tumors of infiltrating ductal carcinomas (22 primary tumors with metastasis and nine primary tumors without known metastasis), 22 matched nodal metastases, 10 fibroadenomas and five normal breast tissues (obtained from reduction mammoplasty).
A head CT and MRI demonstrated an infiltrating lesion in the right orbit along the inferior and lateral compartment of the orbit involving the intra- and extra-coronal space.
In some circumstances, CD4 +and CD8 +T cells were rendered inactive in tumor-bearing hosts [ 8 ] . The inactivation of CD4 +T cells has been attributed either to the tumor cells themselves or to bone marrow-derived cells [ 9 10 11 ] , whereas antigen ignorance or loss of memory have been postulated to underlay that of CD8 +T cells [ 12 13 ] . Other studies have suggested that tumor cells can secrete immunosuppressive factors such as TGF-β or express Fas ligand to induce apoptosis of infiltrating lymphocytes [ 14 15 16 ] . Furthermore, the tumor vasculature appears to be quite different from normal blood vessels, in terms of structural organization, interstitial pressure, and flow patterns [ 17 ] , and in reduced lymphocyte and natural killer cell homing and adhesion [ 18 19 20 21 ] . The existence of significant barriers to effective immunological destruction is further illustrated by a mouse model of concurrent multistage tumorigenesis and anti-oncogene autoimmunity, wherein progenitor dysplastic lesions are infiltrated and disrupted, while solid tumors are not [ 22 ] . The hypothesis is that the microenvironment of certain types of solid tumor can serve to locally suppress T cell infiltration.
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