Example sentences for: inaccessibility

How can you use “inaccessibility” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, extending similar approaches to solid tumor oncology is technically and clinically challenging due to relative inaccessibility of tumor tissue and difficulties in obtaining samples at multiple time points.

  • In contrast, immunoprecipitation with HA antibodies failed to precipitate both Csn1p-3HA and Pcu3p-Myc, potentially due to inaccessibility of the C-terminal 3HA tag of Csn1p within the CSN complex (data not shown).

  • Interestingly, in central India the largest state in the country, also contributing highest number of malaria cases (23%) in the country [ 26 ] , the usual practice under NAMP is to provide radical treatment (Chloroquine and Primaquine) to all fever cases during monsoon and post monsoon season in tribal villages due to inaccessibility.

  • Second, the final maturation of the 20S proteasome resulted from the assembly of two half proteasomes into the four stacked ring structure could trap the already bound Smad1 inside the proteasome for rapid degradation or lead to the dissociation of Smad1 from mature 20S proteasome due to the inaccessibility of Smad1 binding site on the incorporated HsN3.

  • The degradation of Smad1 by proteasome is reported in a separate study [ 39 ] . The dissociation of Smad1 from the mature 20S proteasome could be due to the competition of Smad1 binding by a 19S regulator protein or simply due to the inaccessibility of the binding site on HsN3 when two half proteasomes assembly into the mature proteasome.

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