Example sentences for: in-frame

How can you use “in-frame” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Even though the library was biased at the DNA level to avoid stop codons (see Methods), roughly one third of the clones were expected to contain in-frame stop codons within the insert, thus producing a truncated GFP molecule containing only the first 157 amino acids of GFP followed by C-terminal peptides of variable length up to 15 amino acids.

  • A potential translation initiation codon in the NotI/BamHI fragment (3 kb) of clone 4B1 starts an open reading frame that encodes a polypeptide sequence highly homologous to the first six transmembrane domains of the human EP2 receptor [ 20 ] . The amino acid sequence of the open reading frame in the NotI fragment (6 kb) of clone 6A was homologous to the seventh transmembrane domain (TMD VII), followed by a short C-terminal tail and an in-frame stop codon.

  • This created an open reading frame of 1,083 base pairs with an in-frame TGA stop codon.

  • The longest BTBD1 cDNA clone obtained from two-hybrid screening (3196 bp) contains an ORF that encodes a 482 aa protein starting with an ATG that is preceded by an in-frame stop codon.

  • 7%), which is consistent with the interpretation that all in-frame insertions produce a fluorescent protein.


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