Example sentences for: in-frame

How can you use “in-frame” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • First, pBS-NFATp(391-583) was created using single-stranded pBS-KS +-NFATp(NdeI) for site-directed mutagenesis with two oligonucleotides: a unique in-frame ATG codon contained in an Nde I site was created in place of the codon for amino acid 390 using an oligonucleotide of sequence 5'-CATCTGCAGCATCCATATGACTGCATCCCTC-3' and a stop codon was created in the NFATp cDNA after amino acid 583 using an oligonucleotide of sequence 5'-GTTGAAAGACAATAAACAGAATTCTGCCTGGTCTATG-3'.

  • Multiple in-frame exons in a continuous ORF were always considered part of a single gene, an approach that tends to consolidate exons rather than create spurious additional genes.

  • The C/EBPβ mRNA contains three in-frame methionines which give rise to three different translation products: p38, p35, and p20-C/EBPβ [ 21].

  • The discovery that all of the in-frame insertions in α s produced truncated fluorescent fusion proteins suggested that we could identify in frame insertions by transiently expressing all of the transposed clones and visually screening them for fluorescence.

  • Deletion of one EGF-like domain due to exon skipping, especially in the region between exon 24 and 32, usually causes severe neonatal-onset MFS [ 8 24 25 ] . Similar deletions in other regions of fibrillin-1 may also result in early onset of cardiovascular symptoms [ 8 ] . Patient 1, described here, had a genomic deletion of exons 42 and 43 that results in an in-frame deletion of part of the 5th LTBP-like domain and the adjacent downstream cbEGF-like domain.


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