Words similar to immunodominant
Example sentences for: immunodominant
How can you use “immunodominant” in a sentence? Here are some example sentences to help you improve your vocabulary:
injections of the immunodominant G7 peptides (GAD 206-226/217-236/286-300) or of the additional GAD65 peptides identified in NOD.PD mice (I-A NOD/PD) (GAD 333-345/K458-470R) in IFA [ 5 ] . As noted in the background section, PD peptides are not immunodominant in NOD mice.
In accord with these results, immunization of the NOD mice with PD peptides produced a less robust specific IgG1 antibody response than did immunization with the immunodominant G7 peptides (see below).
In the present study, we show that anti-peptide autoantibodies and fatal anaphylactic reactions can be elicited by immunodominant GAD65 peptides in NOD mice that have been injected with these peptides intraperitoneally in incomplete Freund's adjuvant (IFA), as part of an attempt to induce "tolerance" and prevent the spontaneous development of T1DM.
It was of interest that the unmodified protease induces antigen-specific IgG in the absence of detectable immunodominant T cell epitopes.
However, in the thymus a splice variant results in the lack of thymic expression of an immunodominant peptide.