Example sentences for: immunodominant

How can you use “immunodominant” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, the incidence of anaphylactic shock in mice immunized and challenged with PD peptides was significantly lower than that in mice immunized and challenged with immunodominant G7 peptides (P = 0.0058 by Fisher's exact test).

  • It was of interest that the unmodified protease induces antigen-specific IgG in the absence of detectable immunodominant T cell epitopes.

  • In the present study, we show that anti-peptide autoantibodies and fatal anaphylactic reactions can be elicited by immunodominant GAD65 peptides in NOD mice that have been injected with these peptides intraperitoneally in incomplete Freund's adjuvant (IFA), as part of an attempt to induce "tolerance" and prevent the spontaneous development of T1DM.

  • In accord with these results, immunization of the NOD mice with PD peptides produced a less robust specific IgG1 antibody response than did immunization with the immunodominant G7 peptides (see below).

  • Of the mice immunized with the PD peptides, that are not immunodominant in NOD mice, 43% (3/7) developed anaphylactic shock at the time of challenge with PD peptides (Table 1).


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