Words similar to imd
Example sentences for: imd
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NF-κB Activation: The Toll and Imd Pathways of Drosophila
The effector NF-κB transcription factor of the Imd pathway is Relish, which upon immune activation is cleaved by the Dredd caspase (Figure 2).
Using a combination of the RNA interference approach of silencing gene function and a high-throughput cell culture assay, Foley and O'Farrell (2004) report the identification of two new conserved members of this Imd pathway: Sickie is a novel protein required for Relish activation, and Defense repressor 1 is a novel inhibitor of the Dredd caspase.
Toll pathway were identified in earlier genetic screens for developmental mutants, those in the Imd pathway have been the focus of more recent studies, mainly in the context of