Words similar to ii-iii
Example sentences for: ii-iii
How can you use “ii-iii” in a sentence? Here are some example sentences to help you improve your vocabulary:
The present studies show EC coupling recovery by a frame-shift mutant of α 1S due to protein-protein complementation of the N-terminal and C-terminal halves of α 1S . The N-terminal half houses repeats I and II with the adjoining cytosolic loop and the C-terminal half houses most of the II-III loop, along with repeats III and IV with the adjoining loop.
This result is entirely consistent with the identification of the II-III loop as critical for enhancement of L-type Ca 2+current expression by the RyR1 [ 38 ] . However EC coupling, per se, can clearly proceed with a cut in the II-III loop.
To confirm expression of the C-terminus half of α 1S in cells transfected with fs-α 1S , we used the II-III loop polyclonal antibody SKI [ 34 ] directed against epitope Ala739-Ile752 which is downstream from Met701.
Hence, a premature stop codon in the II-III loop upstream of M701 may not necessarily cause a loss of DHPR function because in these cases, function would be recovered by complementation between protein fragments expressed by the same cDNA.
The HindIII-XhoI fragment (nt 2228 to nt 2878) encompasing the II-III loop was subcloned into pCR 2.1 TOPO TA (Invitrogen, CA) and this plasmid was further used for PCR reactions.
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