Words similar to ii-iii
Example sentences for: ii-iii
How can you use “ii-iii” in a sentence? Here are some example sentences to help you improve your vocabulary:
To confirm expression of the C-terminus half of α 1S in cells transfected with fs-α 1S , we used the II-III loop polyclonal antibody SKI [ 34 ] directed against epitope Ala739-Ile752 which is downstream from Met701.
6Cshows that the II-III loop antibody recognized the C-terminus half when cells were transfected with fs-α 1S but not when myotubes were transfected with fs-α 1S M701I.
This result is entirely consistent with the identification of the II-III loop as critical for enhancement of L-type Ca 2+current expression by the RyR1 [ 38 ] . However EC coupling, per se, can clearly proceed with a cut in the II-III loop.
The present studies show EC coupling recovery by a frame-shift mutant of α 1S due to protein-protein complementation of the N-terminal and C-terminal halves of α 1S . The N-terminal half houses repeats I and II with the adjoining cytosolic loop and the C-terminal half houses most of the II-III loop, along with repeats III and IV with the adjoining loop.
Earlier studies in the voltage-gated Na +channel had shown that pore function was not compromised when the II-III linker or III-IV linker was cut and the two fragments were coexpressed each in a separate vector [ 37 ] . We would thus conclude that in the case of the Ca 2+channel, an intact II-III loop is essential for this function since neither fs-α 1S nor the combined expression of the two truncated fragments (not shown) was able to rescue Ca 2+current.
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