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Example sentences for: ii-

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Interestingly, both IFN-γ and TNF-α are prominent in the pathogenesis of autoimmune diseases in general; the former by activation of local auto antigen presentation to appropriate T cells, and the latter by mediation of inflammatory tissue damage [ 68 ] . Apparently TNF-α plays a central role in the chronic release of highly arthritogenic II-1 [ 69 ] , and thus serves as a major factor in the pathogenesis of rheumatoid arthritis (RA) [ 69 ] . Recent studies show that treatment with anti-TNF-α gives significant clinical improvement in RA [ 70 ] . Thus our findings in aged individuals of a prominent CD8 +CD28 -T cell subset with enhanced ability to produce TNF-α, may assume clinical relevance.
pJC14 was a Hpa I- Bsp EI deletion (309 bp) of pJC10, and pJC15 was a Bgl II- Bsp EI deletion (150 bp) of pJC10.
To make pJC13, we removed the Hinc II- Bgl II fragment (602 bp) from pJC10.
pJC18 was a Hinc II- Hinc II deletion (443 bp) of pJC4, and pJC19 was a Bsa BI- Bgl II deletion (262 bp) of pJC4.
Plasmid pJC12 was a Hinc II- Hinc II deletion (443 bp) of pJC10.